Compare Dicloberl and Diclofenac | Determine the best
Diclofenac and Dicloberl are among the most sought-after drugs from the group of nonsteroidal anti-inflammatory drugs (NSAIDs). They have more in common than differences, so we tried to make out which tool is more popular and why. So, which is better - Dikloberl or Diclofenac and how they differ.
Features Diclofenac
Diclofenac refers to nonsteroidal anti-inflammatory drugs that are prescribed for pain relief and the elimination of inflammation. The main active ingredient is diclofenac sodium.
Available in several forms:
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tablets of 25, 50 and 100 mg;
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gel 1%, 3% and 5%;
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suppositories of 50 and 100 mg;
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a solution of 25 and 75 mg;
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spray 40 mg / ml;
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drops of 0.1%.
The tool inhibits the production of substances that are involved in the appearance of edema, exudate, pain, has a weak antipyretic effect. Especially often the drug is prescribed for diseases of the musculoskeletal system. Diclofenac cope with stiffness in the joints, removes swelling. Effective after injuries and surgeries.
Dikloberla Features
Dicloberl contains a similar active ingredient - diclofenac sodium.
The drug is available in the following forms:
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50 mg tablets;
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75 mg solution;
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50 mg rectal suppositories;
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100 mg long-acting capsules.
Prescribed medication for the symptomatic reduction of pain. Especially effective for rheumatism. Anti-inflammatory activity means it can be used to eliminate non-infectious inflammatory lesions of the skin, joints, internal organs.
Indications for use
The drugs belong to the same pharmacological group, so the indications are almost the same. However, it is worth considering each tool separately.
When is Dicloberl prescribed?
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arthritis, gout;
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ankylosing spondylitis;
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various inflammatory disorders of the spine;
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degenerative diseases of the spine;
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inflammatory processes of soft tissues;
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swelling with pain.
Dikloberl is a symptomatic drug. This means that it is prescribed for various diseases in order to eliminate pain and inflammation, but it does not affect the underlying disease. This also applies to Diclofenac. They cope well with this task.
Diclofenac solution is used for short-term therapy for pain of different nature. Most often it is arthritis, neuralgia, lumbago, osteoarthritis. Candles and tablets are used to reduce pain in many diseases of the joints and spine. Gel and ointment used in inflammatory and degenerative processes of the musculoskeletal system. They help to cope with pain after injuries.
Due to the fact that the drug is quite strong it is used in the form of candles and tablets for pain relief in malignant processes.
Contraindications
Both drugs (all forms) can not be prescribed with intolerance to the active ingredient and excipients, as well as allergies to other NSAIDs.
Contraindications to the use of different forms of Diclofenac:
Solution and tablets. Contraindicated in gastric ulcer and 12 duodenal ulcer, internal bleeding of the digestive tract, impaired blood, aspirinovoy asthma. Medicines are not prescribed for children. It is used with caution in anemia, congestive heart failure, high blood pressure. For the at-risk group, which includes the elderly and people with severe kidney disease, an individual dosage is selected.
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Suppositories. Additionally - for hemorrhoids, anal fissures, for children up to 16 years.
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Ointments and gels. Additionally - age up to 6 years, open wounds on the skin.
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Eye drops. Additionally - up to 2 years, transferred herpetic keratitis.
During pregnancy, it is extremely undesirable to take it, because it suppresses the production of prostaglandins, which adversely affects the development of the fetus. Research suggests the risk of heart defects and miscarriage in the early stages. In the late period of gestation, the development of kidney dysfunction, lack of water, and kidney failure is possible.
Diclofenac is not prescribed during pregnancy planning and during gestation.
Dikloberl has the following contraindications:
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history of an allergic reaction to any NSAIDs;
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pathologies of hematopoiesis of unknown origin;
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internal bleeding, including those in the past;
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severe malfunctions in the kidney and hepatobiliary system;
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severe heart failure;
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late pregnancy.
The tool can be appointed according to strict indications in the first and second trimesters of gestation. The last 3 months of pregnancy, this drug is contraindicated.
Possible adverse reactions
Admission of NSAIDs is strongly reflected in the state of the gastrointestinal tract, the mucous membrane suffers, especially if there are already some diseases.
Possible side effects of taking Diclofenac:
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Gastrointestinal tract - dry mouth, nausea, bloating, pancreatitis, abdominal pain, cirrhosis, peptic ulcer, jaundice, diarrhea or constipation;
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NA - headache, anxiety, insomnia, daytime sleepiness, meningitis, nightmares, depression;
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the senses - hearing loss, tinnitus, blurred vision, change in taste, double vision;
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skin manifestations - hair loss, toxic dermatitis, minor hemorrhages, sun intolerance, urticaria, eczema, rash;
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disorders of the genitourinary system - the appearance in the urine of protein, oliguria, nephritis, renal failure, edema;
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respiratory organs - bronchospasm, laryngeal edema, cough;
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others - a burning sensation in the area of drug administration, mucous discharge after using a candle, an allergic reaction.
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With long-term use of the drug often causes unpleasant reactions from the gastrointestinal tract. Patients note stomach pain, indigestion, diarrhea.
Probable side effects of taking Dicloberla:
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Gastrointestinal tract - peptic ulcers and their perforation, diarrhea, bloating, pain in the stomach, the appearance of blood in the feces, colic, intestinal bleeding;
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CAS - swelling, a sharp increase in blood pressure, heart failure, increased risk of heart attack, heartbeat;
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blood and lymphatic system - hemolytic anemia, thrombocytopenia, agranulocytosis, pancytopenia;
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neurological manifestations - tremor, convulsions, disorientation, memory impairment.
Dikloberl has many other side effects that you must be sure to get acquainted with before using the medicine. They develop not often, usually with long-term treatment.
The risk of long-term use of NSAIDs
A study published in the medical publication Lancet says that taking diclofenac sodium increases the risk of developing cardiovascular diseases. At the same time the probability increases when smoking and excess weight.
A paper published in the journal PLOS Medicine says that diclofenac sodium increases the likelihood of a heart attack by about 40%. This applies to long-term medication. By danger, it was compared with the drug "Vioxx", which was banned in 2004.
Method of administration and dosage
NSAIDs can be used one-time to eliminate pain or course depending on the disease and the severity of its manifestations.
Features of the use of different forms of Diclofenac (standard doses, prescribed by a doctor):
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Solution. Introduced intramuscularly. A single average dosage is 75 mg. Repeated administration is possible after 12 hours. It usually takes 2 days, after which it is prescribed suppositories or pills.
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Suppositories are applied rectally, are injected into the rectum after emptying. Assigned to 100 mg once or 50 mg 2 times a day.
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Ointment and gel are applied to the skin, evenly distributed over the affected area. They are used 3-4 times a day.
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Drops are prescribed up to 5 times per day with a course of no more than 4 weeks.
An overdose is possible when using the solution, tablets and suppositories. It manifests itself by clouding of consciousness, vomiting, dizziness, respiratory failure. With these symptoms, you must stop treatment and immediately consult a doctor.
Features of the use of various forms Dikloberla:
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Solution. Introduced intramuscularly. The average daily dose is 75 mg, maximum 150 mg.
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Pills. Accepted with meals. The average dose per day is 50-100 mg for 2 doses.
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Suppositories. The average daily dose is 50-100 mg for 2-3 injections.
Overdose causes symptoms such as headache, dizziness, convulsions, low blood pressure, cyanosis of the mucous membranes, and cyanosis. Treatment is aimed at eliminating the adverse reactions that have occurred.
Independently stop the symptoms of overdose can not. Before visiting the doctor, it is contraindicated to take any drugs.
Cost and analogues
Comparative characteristics of the price and analogues of drugs:
A drug |
Price |
Analogs |
Diclofenac |
20 tablets of 100 mg each - from 80 rubles; Gel 5% 100 g - from 170 rubles; Ampoules 5 pieces - from 55 rubles; 10 suppositories 100 mg each - from 55 rubles |
Bolaren; Diklopar; Afenak-Mr; Voltaren; Dipren; Dolomed; Fanigan; Tilda |
Dickloberl |
Tablets of 20 pieces on 100 mg - from 280 rubles; Ampoules 5 pieces - about 270 rubles; Suppositories of 5 pieces on 50 mg - from 210 rubles |
Not all presented preparations are complete analogues, in some excipients in the composition are different. Self-replacement of drugs is dangerous to health, so you need to first consult a doctor.
What's better
Both drugs are well suited for single use in order to eliminate pain. For intramuscular administration, the best option would be Dikloberl. For the treatment of joints and muscles it is better to use Diclofenac-gel. Dicloberl is considered a more benign drug when you need regular use of nonsteroidal anti-inflammatory drugs.
General characteristics
Preparations have a similar active ingredient, which causes the same effect. Both tools successfully cope with pain. The negative impact on various organs and systems will also be common. Means badly affect the digestive tract and harm the heart. Risks are significantly reduced if one-time medication is taken.
The main differences
The basic difference of drugs - the manufacturer. Dikloberl produced according to a single standard by the Menarini group. Diclofenac is produced by numerous factories in Russia and the CIS.
Another difference can be distinguished by the fact that Dikloberl more gentle and does not provoke thrombosis. Diclofenac can cause thrombosis. If we talk about short-term treatment, the latter is more advantageous in price and availability in different forms.
Dicloberl and Diclofenac are equally effective when used according to indications.Only the attending physician can choose the safest drug in a particular case.