What drug is better than Recognan or Cerakson

Ceraxon and Recognan are drugs from the group of nootropics. They have a positive effect on the higher integrative functions of the brain - they improve mental activity, attention and memory, increase the resistance of cells to hypoxia. Nootropics are prescribed in the recovery period after a stroke and traumatic brain injury, are used in the treatment of vascular pathology of the brain and in other conditions. They are well tolerated and enjoy well-deserved recognition in neurological practice.

We looked into the instructions for use and found out that Cerakson and Rekognan are similar in composition, indications and contraindications. Analysis of clinical studies showed that these drugs do not differ in principle of influence on the human body. They are interchangeable, and in most cases the patient will not notice the difference. The selected drugs differ only in price: Recovered cheaper than Cerakson. Neuroscientists say that in this situation the replacement is justified. Tests have shown that cheap Rekognan is not inferior in effectiveness to Cerakson.

Let's find out when drugs are prescribed, which remedy is better tolerated and whether there are differences in the regimen of administration.

Compare the composition: is there a difference?

The experts of our magazine studied the instructions for the studied nootropics and found out: they have the same composition. The active ingredient of Recognan and Ceraxone is sodium citicoline (1045 mg). Drugs are available in two forms:

1. oral solution;

2. injection.

Ceraxon is an original drug. It is produced in Spain, imported to various countries of the world, including Russia. The cost of the drug depends on the form of release. For 5 ampoules of solution for injection will have to pay 800-1000 rubles. Solution for ingestion is 1500-1800 rubles for 10 pieces.

Rekognan is a generic. It is produced in Russia and contains the same active ingredient as the original, but differs in production technology. Rekognan cheaper - 5 vials of solution for injection will cost 500-700 rubles. The price of the means for oral administration is 1200-1500 for 10 pieces.

How do nootropics work?

When we compare the original drug and the generic, we immediately expect to see the difference. It is known that the original has passed randomized clinical trials, proved to be effective in certain situations. We know how it is transferred - this is confirmed by pharmacological studies. Its high price is justified, because it acts more efficiently and is better tolerated than a generic.

Rekognan is a pleasant exception to the rule. Studies show that the domestic drug is not inferior in effectiveness to a foreign tool. Proved almost the same effect of Rekognan and Cerakson in the treatment of acute disorders. There were no statistically significant differences in the rate of onset of the therapeutic effect.

Rekognan and Cerakson equally affect the state of the nervous system:

1. Restore damaged membranes of nerve cells.

2. They have an antioxidant effect - they prevent the action of free radicals and protect tissues from damage.

3. They affect the mechanisms of apoptosis and prevent cell death.

4. Reduce the amount of damage to brain tissue in the acute period of stroke.

5. Reduce the duration of coma with traumatic brain injury.

6. Reduce neurological manifestations in various brain lesions.

7. Shorten the duration of the recovery period.

The preparations have good bioavailability - most of the active substance gets into the affected tissue and exerts its effect. Only 15% citicoline sodium is eliminated from the body: 3% with the kidneys and 12% with exhaled carbon dioxide through the lungs.

When are they appointed?

Cerakson and Rekognan are shown under such conditions:

1. complex therapy in the acute period of ischemic stroke;

2. recovery from ischemic and hemorrhagic stroke;

3. traumatic brain injury: in the acute period and during rehabilitation;

4. vascular diseases of the brain.

The duration of treatment is at least 3 weeks. In many medical sources, it is indicated that in order to obtain a result, it is necessary to take the drug for at least 6 weeks. The dosage is determined by the doctor based on the severity of the patient's condition.

Is there any effect?

In the scientific environment, the debate about the effectiveness of nootropics in the treatment of brain diseases does not cease. The experts of our journal analyzed scientific articles and found out that the opinions of doctors differ. We present to your attention the most famous work.

An international randomized placebo-controlled trial (ICTUS) showed that citicoline is not effective in treating moderate to severe acute ischemic stroke. 2298 patients from Germany, Portugal and Spain participated in the testing - and this is a fairly large sample.

In the Russian Medical Journal, domestic experts analyzed the results of the ICTUS study and concluded that it is impossible to clearly speak about the low efficacy of citicoline. They stressed that a negative result could be associated not only with the effect of the drug, but also with the overestimated expectations of scientists. They highlighted such aspects:

1. About 67% of the subjects were over 70 years old. At this age, the prognosis of the disease is worse, the risk of complications is higher.

2. The study included patients with severe and moderate course of the disease. In other papers, where mild cases of stroke were included in the sample, the result was better.

3. 46% of patients had systemic thrombolysis, which could distort the results of the study.

4. Russian scientists have concluded that citicoline can be used in patients with ischemic stroke who do not receive thrombolytic therapy (drugs to destroy a blood clot).

5. The Nevronews magazine presented the results of a comparative study of Reconnan and Cerakson. The tests were carried out by specialists of the First St. Petersburg Medical University. They found that both drugs are equally effective in treating the effects of traumatic brain injury.

6. An article was published in the journal “The attending physician” showing the efficacy of Ceraxon in the treatment of chronic cerebral ischemia and dementia.

Perhaps in the coming years, scientists will provide new developments on this topic, and then the question of the effectiveness of citicoline will be closed.

How are they transferred?

Clinical trials show that nootropics are well tolerated and rarely cause side effects. During treatment there can be such undesirable reactions:

1. headache;

2. dizziness;

3. tremor;

4. feeling hot;

5. nausea, vomiting, and diarrhea;

6. insomnia;

7. decreased appetite;

8. dyspnea;

9. numbness of the limbs;

10. lower blood pressure;

11. allergic reaction: itchy skin, rash, anaphylactic shock.

Side effects are rare: less than 1/10000 cases.

In the scientific works devoted to citicoline, there were no significant differences between Cerakson and Rekognan.Both drugs have the same negative effects. There is no evidence that the original Cerakson is better tolerated than the generic Recognan.

Both drugs are not prescribed during pregnancy and lactation, children under 18 are not. Citicoline is not used for hypotension - lowering blood pressure below 100/70 mm Hg. Art.

Cerakson and Rekognan affect the reaction rate and attention. During treatment, you can not drive a car, work with moving machinery, etc.

findings

Comparison of drugs showed:

1. Ceraxon and Rekognan contain the same active ingredient - citicoline sodium. The form of release of drugs is the same.

2. Both tools successfully cope with violations of cerebral circulation and the consequences of traumatic brain injury. Can be used in the treatment of ischemic and hemorrhagic stroke.

3. Both drugs are equally well tolerated and rarely cause side effects.

4. Ceraxon is an original foreign drug, and it costs more than the Russian generic Cerakson.

Before choosing a drug, consult your doctor. Remember that self-treatment is dangerous and can worsen the condition. Ceraxon and Rekognan are drugs from the group of nootropics. They have a positive effect on the higher integrative functions of the brain - they improve mental activity, attention and memory, increase the resistance of cells to hypoxia. Nootropics are prescribed in the recovery period after a stroke and traumatic brain injury, are used in the treatment of vascular pathology of the brain and in other conditions. They are well tolerated and enjoy well-deserved recognition in neurological practice.