20 best antibiotics according to the doctor
Top antibiotics rating
Nomination | a place | Name of product | price |
The best antibiotics for sore throat, bronchitis and cough | 1 | Flemoxin Solutab | 326 ₽ |
2 | Amoxiclav | 466 ₽ | |
3 | Sumamed | 400 ₽ | |
4 | Levofloxacin | 359 ₽ | |
5 | Suprax | 818 ₽ | |
The best antibiotics for sinus | 1 | Sultasin | 64 ₽ |
2 | Macropene | 331 ₽ | |
3 | Rocephin | 501 ₽ | |
4 | Abelox | 332 ₽ | |
5 | Isofra | 283 ₽ | |
The best antibiotics for children | 1 | Cephalexin | 89 ₽ |
2 | Clarithromycin | 442 ₽ | |
3 | Lincomycin hydrochloride | 154 ₽ | |
4 | Roxithromycin | 147 ₽ | |
5 | Furadonin | 177 ₽ | |
The best broad-spectrum antibiotics | 1 | Vilprafen Solutab | 700 ₽ |
2 | Zinforo | 28 302 ₽ | |
3 | Invans | 1 650 ₽ | |
4 | Cubicin | 5 747 ₽ | |
5 | Maxipim | 192 ₽ |
The best antibiotics for sore throat, bronchitis and cough
Inflammatory diseases of the upper respiratory tract - one of the most common in clinical practice. Such diseases as sore throat and bronchitis are susceptible to both children and adults. Sometimes these pathological conditions can be caused by viruses, but bacterial infection often also occurs. In this case, it is necessary to use antibacterial drugs (antibiotics). It should be recalled that antibiotic therapy should be carried out only after a full examination of the patient, diagnosis and testing the sensitivity of the flora to a particular antibiotic.
A sharp increase in body temperature, an increase in signs of general intoxication (weakness, headache and muscle pain, dizziness), cough with a discharge of purulent sputum may indicate the accession of a bacterial infection. This article will review the ranking of the most affordable and effective antibiotics for angina, bronchitis and cough in adults.
Flemoxin Solutab
Rating: 4.9
Antibiotic Flemoksin Solutab (Amoxicillin) from the group of aminopenicillins, is available in the form of soluble tablets of 20 pieces per pack. There are several basic dosages: 0.125g, 0.25g, 0.5g, 1.0g. Amoxicillin is the main active ingredient that inhibits the growth and development of many gram-positive and gram-negative bacteria (pyogenic cocci, which most often provoke inflammatory diseases of the upper respiratory tract).
However, this antibiotic got into the rating because it is used not only for sore throat and bronchitis - it can also inhibit the growth of some intestinal bacteria, which provoke intestitis and inflammatory processes in the urinary organs.
Advantages and disadvantages
The main advantages of this medication is a quick and complete absorption in the gastrointestinal tract, a pleasant taste, the possibility of use from an early age. Another advantage of the drug Flemoksin Solutab is that it can be drunk both before and after meals (and even during meals). With the proper use of this antibiotic, a pronounced therapeutic effect develops from the first hours. But you can notice it in a few days.
A number of disadvantages include, first of all, frequent allergic reactions that occur after using the drug, high cost (relative to analogues), as well as the inability to inhibit the growth of bacteria that produce an enzyme such as beta-lactamase (this enzyme destroys penicillins). In general, the advantages of Flemoxin are much more, therefore this remedy is often used in inflammatory processes that occur in the upper respiratory tract. Price - 200 rubles.
Amoxiclav
Rating: 4.8
This is an antibiotic from the same group as Flemoksin Solutab - it belongs to the aminopenicillin group. Available Amoxiclav (amoxicillin and clavulanic acid) in the form of tablets of 14 pieces per pack. There are different dosages of this antibiotic: 0.25g, 0.5g, 0.875g, however, it should be noted that the amount of clavulanic acid remains unchanged and is 0.125g. The price of antibiotic is 350 rubles.
Advantages and disadvantages
As mentioned above, in addition to the main active ingredient - Amoxicillin, the drug contains clavulanic acid, which plays an important role in the treatment of bronchitis and tonsillitis caused by bacteria that synthesize beta-lactamase. Since this enzyme is capable of destroying penicillins, clavulanic acid blocks it, thereby achieving a more pronounced and rapid effect. Another advantage - the drug has little effect on the functioning of the gastrointestinal tract.
The disadvantages include the fact that Amoxiclav, like all other penicillins, often causes allergic reactions (therefore, prior to their appointment, it is necessary to test for sensitivity). Perhaps a violation of the intestinal microflora and vagina (dysbiosis and dysbiosis), therefore, Amoxiclav is always prescribed together with probiotics.
Sumamed
Rating: 4.8
The antibiotic belongs to the group of macrolides, is available in the form of capsules, tablets, suspensions and lyophysilate for injections. Approximate price is 400 rubles. Sumamed (Azithromycin) actively suppresses the production of bacterial proteins of the cell wall, which prevents the rapid proliferation of bacteria. Sumamed is often used to treat chronic tonsillitis (sore throat) and prolonged bronchitis. It is especially recommended to take it to those patients who, due to individual intolerance, cannot be treated with penicillin antibiotics.
Advantages and disadvantages
The advantage of Sumamed is that it is an extremely active drug that does not require frequent use, and it is rightfully ranked. It has a good effect of accumulation in organs and tissues of the body, a rather long period of disintegration and half-life, and also affects not only aerobic bacteria (which develop in the presence of oxygen), but also anaerobic (multiplying without access of oxygen). Sumamed provides an opportunity to treat inflammation of the upper respiratory tract, if they are caused by chlamydia or mycoplasma. The antibiotic is usually well tolerated (even with long courses), rarely causes hypersensitivity reactions. The disadvantage of this drug is its high cost.
Levofloxacin
Rating: 4.7
The drug is available in the form of tablets and solution for injection. Levofloxacin is an inexpensive, but quite effective drug, the price of which is 100 rubles. The antibiotic belongs to the group of fluoroquinolones, acts primarily on the DNA of bacteria, thereby preventing them from multiplying. It is used if the patient has an allergic reaction to penicillins and macrolides, which does not happen very often. Levofloxacin acts on a large number of different bacteria, this is due to its high efficiency.
Advantages and disadvantages
The main advantage, as already mentioned, is the wide spectrum of action of this antibiotic, so it can be used in cases where angina or bronchitis is caused by several types of bacteria (mixed infection). The antibiotic is rapidly absorbed and metabolized, instantly acting on the genetic apparatus of microorganisms. Another undoubted advantage - low price.
However, a broad spectrum of action is not only a virtue, but also a disadvantage of Levofloxacin. Killing pathogens, the drug also destroys the body's natural microflora.Therefore, this drug can be used only in short courses and only under the supervision of a physician. Otherwise, there is a high probability that dysbacteriosis or fungal lesions of the skin and mucous membranes will develop. It is not uncommon when, against the background of Levofloxacin intake, allergic reactions develop, therefore it is not recommended to prescribe the agent in childhood. However, the antibiotic was included in the rating as a representative of active and modern fluoroquinolones, and side effects are an inevitable consequence of any active drug.
Suprax
Rating: 4.7
The antibiotic belongs to a series of cephalosporins and is available in the form of capsules of 0.2 and 0.4 g. Suprax (Cefixime) inhibits the reproduction of various kinds of bacteria, suppressing their division in the early stages. This remedy is used (like all other cephalosporins) for bronchitis and sore throat only if the patient has a hypersensitivity reaction to all the above described groups of drugs. Often, Suprax is used for the complex therapy of prolonged bronchitis or tonsillitis caused by several types of microorganisms.
Advantages and disadvantages
The main advantage is the effectiveness and speed of the antibiotic. It can even be used in childhood (Suprax is prescribed if the patient goes to the hospital late, and the infection progresses and urgent help is needed). The antibiotic is very quickly absorbed and begins to act, and a long half-life allows you to use it 1-2 times a day.
The disadvantages of Suprax are its high allergenicity, as well as the need for maintenance therapy in the form of immunostimulants and probiotics, which is aimed at preventing mycoses (fungal infections) and dysbacteriosis. The price is quite high and amounts to 630 rubles.
The best antibiotics for sinus
Sinusitis is a disease that is an inflammation of the paranasal sinuses, which is accompanied by arching pain, fever and purulent discharge from the nose. When these symptoms appear, you should immediately consult a doctor to carry out the necessary research and diagnosis. Since in most cases, sinusitis is caused by bacteria, antibiotics are a mandatory component of treatment. However, they are used only if the patient has a weakened immune system and the body cannot cope with this infection on its own.
The need to use antibacterial drugs for prolonged sinus is justified by the fact that infection from the sinuses can get into the cranial cavity or spread by hematogenous (through blood vessels) to other organs. If a patient is not treated in time, there is not only the risk of complications, but also the likelihood of the disease becoming chronic, which is fraught with frequent inflammatory processes in the upper respiratory tract. This rating is based on the preferences of the professional community of doctors.
Sultasin
Rating: 4.9
An antibiotic from the group of protected aminopenicillins, which is available in powder form in vials (1.5 g each). It is diluted with saline or local anesthetics and injected into the body by injection (intravenous or intramuscular).
The mechanism of action of protected aminopenicillins is that they bind to receptors on the surface of bacterial cells (there are no such receptors in the body, therefore the drugs in this group do not act on healthy cells and tissues). Thereafter, aminopenicillins inhibit the production of proteins, which are part of the bacterial cell wall. In addition, Sultasin (Ampicillin and Sulbactam) affect the enzyme penicillinase (beta-lactamase), which is produced by some strains of bacteria and inhibits the activity of the main active ingredient.As a result, even resistant bacteria die under the action of Sultasin.
Advantages and disadvantages
The main advantages of this drug is the effectiveness and speed of action, and the antibiotic can be used to treat sinusitis in childhood. Another advantage is the low price, which is 70 rubles.
The disadvantages of protected aminopenicillins (including Sultasin) are the rapid half-life (the drug should be used frequently) and frequent allergic reactions. In addition, Sultasin affects the gastrointestinal tract and often causes dysbiosis.
Macropene
Rating: 4.8
Macropen (Midecamycin) is a macrolide antibiotic that has a bacteriostatic action (actively inhibits the growth of microorganisms for a long period of time). It is sold as an oral powder, but 0.4g tablets are most common (16 pieces per pack).
Advantages and disadvantages
Since the drug has a bacteriostatic effect, it can be used for sinus, prone to prolonged or chronic course. Macropen is one of the most preferred medicines if the patient has an allergic reaction to penicillins (and this happens quite often), and this allowed him to get into the rating. Macropene rarely causes any side effects and hypersensitivity reactions; when it is taken, intestinal dysbacteriosis occurs much less frequently. Another advantage is the long half-life, so sometimes 1-2 pills per day are enough. The drug is suitable for the treatment of mixed infections (caused by several types of microorganisms).
The disadvantages of the drug can be attributed to the relatively high cost, which today is 220 rubles. It is undesirable to use Macropen during pregnancy, lactation and in early childhood (in such situations it is used only in extreme cases).
Rocephin
Rating: 4.7
The cephalosporins antibiotic has long been used to treat various inflammatory diseases, including sinusitis. The drug has a bactericidal action (destruction of microorganisms), while it is active to a much larger number of pathogens than the above-described penicillins and macrolides. Rotsefin (Ceftriaxone) is produced as a powder in 1 g bottles. It is intended for intramuscular and intravenous administration, having previously dissolved the contents of the bottle in physiological saline or a local anesthetic.
Advantages and disadvantages
As already mentioned, rocephin can affect a large number of different microorganisms. Moreover, it has a long half-life, so the patient does not need to worry about taking the medicine every few hours - usually 1-2 injections are enough per day. This fact allowed Rocefin to be included in the rating for compliance, that is, for ease of use, which leads to a high patient adherence to treatment.
Of the disadvantages, the most significant is the fact that penicillin intolerance is often combined with an allergy to cephalosporins, so a test must be carried out before use. Another disadvantage is the fact that Rocephin does not inhibit beta-lactamase, which some bacteria synthesize as a protective enzyme. The price of the drug is quite high and is 450 rubles. During pregnancy, while breastfeeding and in early childhood, Rocephine should be used with extreme caution. Requires the appointment of maintenance therapy, which will reduce the risk of dysbiosis and fungal infections.
Abelox
Rating: 4.6
Antibiotic Avelox (Moxifloxacin) belongs to the 4th generation (the most modern) of fluoroquinolones, and this allows him to lead the rating in this group.This group of antibiotics is 100% synthetic - such substances are not found in the environment, but are created artificially. Avelox is available in the form of tablets of 0.4 g and a solution for injection.
Advantages and disadvantages
The main advantage and reason why Avelox is often used for antritis of unexplained etiology (origin) or for mixed infections (including those caused by mycoplasmas and chlamydia) is due to the fact that this drug has a wide spectrum of action and can in just a few days required therapeutic effect.
Disadvantages at Avelox is also enough. The medicine is foreign to the body (as already mentioned, it is completely synthetic), therefore, allergic reactions and dyspeptic phenomena (nausea, vomiting, diarrhea) can often be observed. In addition to motility of the gastrointestinal tract, Avelox affects the intestinal flora - it inhibits it and leads to the development of dysbiosis, which is often joined by secondary infections (for example, fungal infections). The drug can not be used during pregnancy, sometimes it is used to treat sinusitis in children, but this requires serious indications. The price of the antibiotic is 600 rubles, which relates it to fairly expensive drugs.
Isofra
Rating: 4.5
This is a local antibiotic that comes in the form of a nasal spray in 15ml vials. Isofra (Framycetin) refers to aminoglycosides, which have a pronounced bactericidal action. Antibiotic is widely used in clinical practice for the treatment of acute and chronic sinusitis, which are caused by aerobic bacteria (breeding in an oxygenated medium) and anaerobes (developing in anoxic space). However, the drug in clinical practice will be used only intranasally, as it is recognized as a fairly toxic compound (especially when it gets on the mucous membranes of the gastrointestinal tract).
Advantages and disadvantages
The main advantage is a short course of treatment, which is 3-7 days. However, this duration of therapy does not affect the effectiveness of Isofra. This tool can be used for the treatment of adults, and in the treatment of sinusitis, which arose in childhood. At the same time, the antibiotic is almost not absorbed into the blood, so it does not affect the functioning of the liver, stomach and intestines, does not cause a decrease in immunity and dysbacteriosis, and this allows us to assign the drug a high place in the safety rating.
The disadvantages of using Isofra include the fact that this drug does not affect pneumococci and streptococci, which are often the causative agents of prolonged sinusitis. Therefore, if the symptoms do not decrease after a week of use, you will have to prescribe another antibacterial drug. The cost of the drug is 250 rubles.
The best antibiotics for children
At the moment, a large number of antibiotics can be bought over the territory of Russia without a prescription. People are accustomed to taking antibacterial drugs as drugs that help with almost any disease, but this is not so. Antibiotics are really effective only when the disease is triggered by bacteria, with the viral origin of the pathology, such drugs can only aggravate the child's condition, just as in the case of the disease caused by protozoa, for example, amoebic dysentery.
Antibiotics for children can be used only if they are prescribed by the doctor after all necessary examinations. In this case, the doctor must take into account the individual characteristics of the body, the nature of the course of the disease, as well as all available indications and contraindications. It is advisable to prescribe antibacterial drugs that do not affect intestinal motility and the normal flora of the body.
Cephalexin
Rating: 4.9
An antibiotic from the group of beta-lactams, namely it refers to cephalosporins. Cefalexin is available in the form of capsules of 0.5 g, 16 packs each. The drug has a pronounced bactericidal action (destroys microorganisms). It is often used in inflammatory diseases of the upper respiratory tract, urinary system, skin and subcutaneous fat, ENT organs, and the musculoskeletal system. Its application is possible already from the neonatal period, however the course and dosages are selected individually, taking into account the age and weight of the child. This permission to use the drug in newborns significantly increases the safety rating of this drug.
Advantages and disadvantages
The advantage of Cefalexin is its low price, which today is 65 rubles. It can be used from the first month of a child’s life, even with long-lasting and hard-flowing infections. It does not require taking the drug too often - 1-2 capsules per day are enough. Cefalexin has a pronounced effect on a wide range of bacteria, inhibiting their reproduction. It can be used as a first-line drug for pneumonia. It is one of the few cephalosporins that are prescribed in capsules, and not available in injections.
Disadvantages are possible side effects (dyspeptic phenomena: diarrhea, vomiting, nausea, flatulence) and allergic reactions. Caution should be used for the treatment of premature babies with burdened allergic history.
Clarithromycin
Rating: 4.9
Clarithromycin is an antibacterial drug that belongs to a number of macrolides. The antibiotic has a mild bacteriostatic effect, so it is often used for long-lasting infections of the upper respiratory tract, rhinitis, otitis, sinusitis and sinusitis. It is produced in the form of tablets and capsules of 0.25 and 0.5 g. Clarithromycin inhibits the reproduction of pyogenic cocci, mycobacteria and Helicobacter pylori infection, therefore it is often used to treat gastric ulcer.
Advantages and disadvantages
The main advantage of Clarithromycin, as well as other antibacterial drugs from the group of macrolides, is the minimal possibility of side effects. Therefore, the drug can be used in the first year of life of the baby. Another advantage is a course of treatment from 6 to 10 days, while prescribing 2 capsules per day. Rapid absorbability and a long half-life ensures effective action and the achievement of a therapeutic effect in a short time. The price of an antibiotic is average and is 230 rubles.
Disadvantages Clarithromycin can be called low activity compared with other antibiotics (for example, from the group of cephalosporins). Therefore, if ineffective or in the presence of a mixed infection, it is necessary to combine this drug with other antibacterial drugs. This may slightly lower the efficiency rating, which increases safety.
Lincomycin hydrochloride
Rating: 4.8
Lincomycin hydrochloride belongs to the antibiotics from the group of lincosamides. It can have both bactericidal and bacteriostatic effects on a large number of different microorganisms. Lincomycin hydrochloride is available as a solution for injection and in capsules of 0.25g. It is used in inflammatory processes of the skin, upper and lower respiratory tract, bones and joints, heart and blood vessels. The drug is rapidly absorbed from the gastrointestinal tract, and the maximum concentration is reached within a few hours. Actively affects cocci flora, sticks and other types of microorganisms.
Advantages and disadvantages
The advantage is rapid absorption and action of the drug, as well as possible bacteriostatic and bactericidal effects of relatively many groups of microorganisms.The antibiotic is inexpensive, today it can be purchased at a price of 50 rubles.
Lincomycin hydrochloride has some disadvantages. An antibiotic can be used only from 6 years on. It should be prescribed with caution if the patient has chronic diseases of the digestive system, cardiomyopathy and allergic reactions. Lincomycin can lead to the development of dysbiosis and fungal infections of the skin and mucous membranes, so it is recommended to use supportive therapy. The cumulative balance of strengths and weaknesses allows lincomycin to maintain a stable, average position in the ranking of broad-spectrum antibiotics.
Roxithromycin
Rating: 4.7
This is a macrolide antibiotic often used in pediatrics. Roxithromycin is available in the form of tablets of 0.15g for 10 pieces per pack. It is referred to as a broad-spectrum antibacterial drug, so it has found wide practical application. It is used to treat inflammatory diseases of the skin, upper respiratory tract, urinary system, ENT organs, and bones. Roxithromycin is also used in the treatment of childhood infections caused by bacteria, namely scarlet fever, whooping cough, diphtheria. Often used for the prevention of infectious myocarditis with dental interventions.
Advantages and disadvantages
The advantage that increases the rating is a mild bacteriostatic effect, which mainly applies only to pathogenic microorganisms. At the same time, the normal intestinal microflora practically does not suffer, therefore dysbacteriosis and concomitant fungal infections are rare. Practically never Roxithromycin causes allergic reactions. The drug is rapidly absorbed from the gastrointestinal tract and does not require frequent administration. The price of the antibiotic is quite low and amounts to 140 rubles.
Among the disadvantages of Roxithromycin, it is possible to single out a negative effect on the enzymatic activity of the liver, therefore, the antibiotic should not be prescribed for impaired function of this gland. Not recommended for babies under 2 months.
Furadonin
Rating: 4.6
Furadonin (Nitrofurantoin) is a drug with a pronounced antimicrobial activity, which belongs to the class of nitrofuran derivatives. Actively inhibits the proliferation of bacteria by inhibiting the synthesis of RNA and DNA. The most common purpose of Furadonin is in urology, due to its bacteriostatic action, it is used even for long-lasting urinary tract infections (pyelonephritis, cystitis, urethritis). Available in pill form, which must be taken 2-3 times a day (as recommended by the doctor).
Advantages and disadvantages
The main advantage of Furadonin is that the pathogens of urinary tract infections practically do not develop resistance (resistance) to this drug, this increases the efficiency rating with long-term use. Therefore, it can be taken as part of a comprehensive treatment that includes several courses. It is rapidly absorbed in the stomach, enters the blood plasma and binds to proteins, and then begins to act on the nephrons in the kidneys. The price of antibiotic is low and is 75 rubles.
The disadvantage can be called the fact that Furadonin can be used only from 12 years old, before that - according to testimony and with caution. But in this case, it is completely replaceable with furagin. The drug can affect the function of the liver and the gastrointestinal tract as a whole, sometimes causing allergic reactions, neurotic disorders and dyspepsia.
The best broad-spectrum antibiotics
Many inflammatory diseases are caused by bacteria, so the prescription of antibiotics in this case is the primary measure of etiotropic treatment (aimed at the cause of the disease).For the appointment of the most effective antibacterial drug, you need to take the patient's material and do the planting, and then determine the sensitivity of bacteria to certain drugs. However, such an analysis can be done from several days to several weeks, and the patient sometimes needs antibacterial therapy at the time of seeking medical help.
For these purposes, broad-spectrum antibiotics are used. Their essence lies in the fact that they can act on a large number of varieties of bacteria and inhibit their growth. Consider the rating of the most popular drugs.
Vilprafen Solutab
Rating: 4.9
This is an antibacterial drug that belongs to the last generation of the macrolide group. Available in the form of dispersed tablets of 10 pieces per pack with a dosage of 1 g. Vilprafen Solyutab (Dzhozamitsin) in small doses inhibits the growth of bacteria, that is, has a bacteriostatic effect. But in large doses, this antibiotic acts as a typical bactericidal agent (kills microorganisms). It is used to treat many diseases: infections of the upper and lower respiratory tract, urogenital system, lor-organs, skin, sometimes used for gastritis, which is caused by exposure to Helicobacter pylori.
Advantages and disadvantages
The advantage of this drug is that it practically does not affect the intestinal microflora, does not cause dysbiosis. It has a long lasting effect due to the long half-life. Rapidly absorbed in the gastrointestinal tract, and the maximum concentration is reached in the blood within an hour. It is indicated for the treatment of many infections.
The disadvantage is the fact that Vilprafen Solutab penetrates the placenta and can be excreted in milk during lactation. The antibiotic has a fairly high price, which today is 630 rubles.
Zinforo
Rating: 4.9
Zinforo (Cefarolina fosamil) is the fifth, last generation antibiotic of a series of cephalosporins, which has a bactericidal effect. The antibiotic inhibits (inhibits) the growth of both gram-negative and gram-positive bacteria. It affects microorganisms that multiply in oxygen and oxygen-free environments (aerobes and anaerobes). It can be used in some inflammatory processes that are caused by bacteria, namely in the pathology of the skin, upper and lower respiratory tract.
Sufficiently rapidly absorbed, slowly excreted. It does not affect erythrocytes and blood formation, it can have a rather strong effect on the gastrointestinal tract (it suppresses normal microflora). Available in powder form at 0.6g per vial, it must be diluted with saline before administration.
Advantages and disadvantages
The advantage of the drug is its high efficiency - usually a few injections are enough to achieve a therapeutic effect. It can be used in inflammatory diseases when a mixed infection (caused by several infections) is observed.
However, the antibiotic can affect the work of the gastrointestinal tract, disrupting the basic functions of the liver. The drug has a high price, Zinforo is not sold in all pharmacies, sometimes it is quite difficult to buy. With care it is necessary to apply at pregnancy, lactation, at children's age. As with all cephalosporin antibiotics, this remedy does not have a tablet or capsulated form - the drug is used only as an injection. This fact can also sufficiently "downgrade the rating" of the drug, despite its modernity and high efficiency.
Invans
Rating: 4.8
Invanz (Ertapenem) is an antibacterial drug from the group of carbapenems, which belongs to the latest generation of broad-spectrum antibiotics.Available in the form of liofizilat for injection of 20 ml, while one bottle contains 1 g of the active substance. It is used in peritonitis, infectious complications of abortion, pneumonia and other inflammatory diseases of the respiratory tract. Often, Invanz prescribe heavy purulent inflammation of the skin and subcutaneous fat, meningitis, encephalitis and sepsis. Invanz has a pronounced bactericidal action against many microorganisms.
Advantages and disadvantages
Invanz is rapidly absorbed and begins to act on microorganisms - it is administered intramuscularly or intravenously. Often it has a pronounced and rapid effect even in severe bacterial infections (septicemia, long-lasting pyelonephritis). It can act on gram-positive and gram-negative aerobic and anaerobic sticks and cocci. This antibiotic is rightly high in the rankings - after all, it replaced such strong drugs as Tienam and Meronem, and sometimes for difficult patients it remains to “rely” only on such drugs.
The disadvantages of this antibiotic can be called frequent side effects that occur during the use of the drug. In 2-3% causes dyspeptic disorders (nausea, vomiting, diarrhea), sometimes affects the central nervous system, causing headaches, dizziness, visual and hearing disorders. It is not clear how Invanz affects fetal fetal development, so it can be used during pregnancy only in cases where the benefits outweigh possible negative consequences. The price of the drug is high and is 1700 rubles.
Cubicin
Rating: 4.8
Cubicin (Daptomycin) is produced as a lyophilisate for injection at 0.35 or 0.5 g per vial. This antibiotic belongs to the latest generation of lipopeptides (cyclic). Affects mainly the gram-positive bacterial flora, the gram-negative bacteria have a smaller effect. Often used for infections that are caused by antibiotic-resistant Staphylococcus aureus. Assign, for example, in inflammatory processes of the skin and subcutaneous fat, postoperative purulent complications (including myocarditis and endocarditis), sepsis.
Advantages and disadvantages
The main advantage of Kubitsin is its pronounced bactericidal action, which develops 2-3 days after the start of therapy. At the same time, a sufficient therapeutic effect is achieved immediately; further on, it is supported by additionally administered doses of the drug. An antibiotic rarely causes side effects.
Therefore, the drug is indicated for septic conditions, because when there is a high concentration of pathogens in the blood, bactericidal antibiotics cannot be used: the destruction of a large number of microbes in the blood will lead to the release of their antigens and pathogenicity factors into the blood, which can cause infectious-toxic shock. Therefore, the bacteriostatic effect of Kubitsin allowed him to assign him a place in the safety rating.
Disadvantages can be considered that Cubicin must be taken within 10-14 days. As a result of the active suppression of the normal microflora of the body, complications such as fungal infections of the skin and urinary tract, headaches and neurotic disorders can develop. The price is high and is 4900 rubles. Not recommended for use in the age of 18 years, during pregnancy, during lactation, and after 65 years, especially if there are chronic diseases of the gastrointestinal tract, including the liver.
Maxipim
Rating: 4.7
Maxipim (Cefipim) is an antibiotic from the group of 4th generation cephalosporins. Available in powder form in vials of 1g and 0.5g. Before intravenous or intramuscular administration, it must be dissolved in saline or local anesthetics. The drug has a strong bactericidal effect, the maximum concentration in the blood plasma is reached after 2-3 days.The half-life and half-life is long, so 1-2 injections per day are enough. Maxipim is used to treat bacterial infections of the upper respiratory tract, urinary system, genital organs, skin, and generalized processes (candicemia, septicopyemia).
Advantages and disadvantages
The advantages of Maxipima can be considered its high speed of action, as well as the fact that there is no need to do injections more often 2 times a day. At the same time, Maxipim affects a large number of various microorganisms, which often cause hospital and non-hospital infections. The antibiotic can be used in childhood, but this should be done with caution and only under the supervision of a physician. Another plus is the low price, which is 320 rubles.
Disadvantages can be called a negative effect on the intestinal microflora. That is why it is always necessary to prescribe additional therapy, which is aimed at reducing the risk of dysbiosis. Maxipim is not recommended for use during pregnancy. As in the case of other cephalosporins, the popularity rating may be lowered by the absence of oral forms (in the form of tablets and capsules for oral administration).
Attention! This rating is subjective, is not advertising and does not serve as a guide to the purchase. Before buying, you should consult with a specialist.