10 best remedies for thrush
Mushrooms occupy a separate kingdom among living things, distinct from plants and animals. Many of them are parasites that use the human body either as a habitat or as a food source. And, perhaps, the first of the fungi that settle in the body of a newborn are Candida, or representatives of conditionally pathogenic fungi of the genus Candida, and most often it is a type of Candida Flbicans. The term conditionally pathogenic means that in a healthy person with good immunity, this fungus is part of the normal microflora of the intestine, mouth, vagina, and does not cause any inconvenience.
Entry into the composition of normal microflora does not imply intensive reproduction of the fungus. It can simply be detected through various analyzes, and even in small quantities. In the same case, If the fungi begin to multiply rapidly, then we are talking about mycosis, or fungal infection. The term "thrush" reflects the visual picture of the development of the fungus on the mucous membranes. Against the background of bright red hyperemia whitish, with a bluish tint, resembling spilled milk or kefir appear.
In adults, thrush occurs most often as a marker of decreased immunity associated with other infections, and in women of childbearing age, thrush most often develops against the background of bacterial vaginosis, or gardnerella, when the protective properties of the vaginal mucosa are lost and the acidic to alkaline .
In modern dermatology and gynecology, there are a large number of different tools for the treatment of thrush, or vaginal candidiasis. Consider the most popular and effective drugs for the elimination of candidal infections. There are both a means for topical administration, in the form of candles, ointments and gels, and preparations in tablets. The most commonly used and sold are candles.
Rating of the best remedies for thrush
| Nomination | a place | Name of product | price |
| The best candles from thrush | 1 | Klion-D (metronidazole + miconazole) | 348 ₽ |
| 2 | Livarol (ketaconazole) | 391 ₽ | |
| 3 | Betadine (Povidone-iodine) | 394 ₽ | |
| 4 | Zalain (sertaconazole) | 479 ₽ | |
| 5 | McMiror Complex (nystatin + nifuratel) | 699 ₽ | |
| The best ointments and creams for thrush | 1 | Pimafucin (natamycin) | 344 ₽ |
| 2 | Candide (clotrimazole) | 249 ₽ | |
| 3 | Ginofort cream (butoconazole) | 645 ₽ | |
| The best pills from thrush | 1 | Diflucan (fluconazole) | 427 ₽ |
| 2 | Orungal, Irunin, (itraconazole) | 3 115 ₽ |
The best candles from thrush
Preparations administered intravaginally in the form of suppositories have their advantages. This is, above all, the possibility of treating deep-seated foci of fungal infection, through deep administration. In the event that the upper parts of the vagina, the cervix, the mouth of the fallopian tubes and even the tubes themselves are affected, which is rare, then the use of candles is more effective than applying ointments and gels.
Also, candles are usually produced not with a single therapeutic drug, but with several components, which affects the fungus more effectively than ointment.Therefore, in the event that the gynecologist prescribed a patient with vaginal candidiasis of the suppository, this can be considered the most effective way to eliminate the fungal infection. Sometimes the liposoluble candle base is replaced by another, in which case a form for local use is obtained, which are called vaginal tablets.
The technology for candle production is such that at normal, room temperature, they are in solid form, but when inserted into the vagina or into the rectum, when the temperature reaches 36 ° C, the material of the candle begins to melt - basically, it is a mixture of paraffin, with glycerol and gelatin.
What are the benefits of using candles to treat thrush?
- Speed. After the candles melt, the active action of the released components begins, within one or two minutes after the injection;
- action in the local circulatory system of the pelvis. Medicinal substances can affect not only exclusively the mucous membranes. Due to a well-developed capillary network inside the vagina, some of the active substances enter the bloodstream, but, unlike injected drugs, they do not pass through the liver, and sometimes act in lower concentrations, and with greater effect;
- the vast majority of drugs administered in the form of suppositories do not enter the systemic circulation, and therefore in patients with impaired renal excretory function, the method of treatment for thrush with suppositories is the method of choice;
- It is very important that many patients with pathology of the gastrointestinal tract, with gastric ulcer, gastroduodenitis, can not tolerate drugs for oral administration. Candles for thrush are devoid of these shortcomings, and can be used in these persons without restrictions.
For the treatment of thrush apply various groups of candles for vaginal administration. Consider the most effective and affordable drugs, evaluate their advantages and disadvantages.
Klion-D (metronidazole + miconazole)
Rating: 4.9
The drug from thrush Klion-D is a unique complex that contains not only an antifungal drug, but also a remedy for the treatment of anaerobic infection. These are miconazole and metronidazole, which are contained in each tablet for injection deep into the vagina, 100 mg. The tool helps to treat not only thrush, but also trichomoniasis, various pathogenic protozoa, vaginal gardnerella and various conditionally pathogenic anaerobes, such as bacteroids, fuzobakterii and other microbes.
Conditionally pathogenic anaerobic flora often joins in the event of alkalization of the vaginal environment, and facilitates penetration and the process of chronicity for more serious infections. Klion-D is shown in the case of fungal and mixed vaginitis, in which not only the fungal flora reproduces, but also other microorganisms, for example, trichomones. Klion-D is administered one tablet each, which is pre-moistened with water and injected deep into the vagina once a day at night. The course of treatment is 10 days.
Vaginal tablets Klion-d of the Hungarian company “Gedeon Richter” are produced, one package of 10 pieces will cost 280 rubles.
Advantages and disadvantages
The advantage of this drug is a fairly affordable price, the possibility of treating not just thrush, but associated and complex vaginitis, with the presence of anaerobic microflora. This drug is quite effective, and is used for a long time. Side effects include local allergic reactions, such as burning and pain, especially when first injected, the inability to combine Klion-D with alcohol, and in overdose - the development of symptoms such as leukopenia, or a decrease in white blood cells in the general blood count.
But in the event that this drug is used according to indications, and according to the instructions, in most cases the symptoms of thrush disappear after a few days.
Livarol (ketaconazole)
Rating: 4.8
Vaginal suppositories Livarol for thrush contain an effective fungicide, ketoconazole. Each candle dosage of 400 mg, in a package of 5 or 10 candles. Large packaging is available at a price of 550 rubles., Produces the drug domestic pharmaceutical company "Nizhfarm."
Livarol, as well as other antifungal suppositories, is indicated for endometritis as a means of covering, so that the associated fungal flora does not activate, or if there is already underlying candidal vaginitis or thrush. Livarol is applied one candle per day, on average, for 5 days, and for chronic forms of candidiasis - for 10 days. Manufacturers caution against self-terminating treatment if the disturbing symptoms disappear, as this may lead to chronic fungal infection.
Advantages and disadvantages
The advantage of ketoconazole is high efficacy against opportunistic fungi, and the disadvantages include the development of side effects associated with local irritation of the mucous membrane, itching and allergy.
Interaction with other drugs in Livarol is unknown, so it can be used together with tablets and other local drugs without restrictions, due to the low resorptive ability of ketoconazole.
Betadine (Povidone-iodine)
Rating: 4.7
Vaginal suppositories for thrush with betadine are sold in packs of 7 and 14 candles, each of which contains 200 mg of povidone-iodine. A package of 7 candles produced by the Hungarian company Egis can be bought for 300 rubles, and doubled for 14 candles for 485 rubles.
Everyone knows the bactericidal effect of iodine, but for intravaginal administration, of course, the alcohol solution is not applicable, so povidone-iodine is used. One candle corresponds to approximately 20 mg of active iodine. Povidone-iodine destroys E. coli, Staphylococcus aureus, is active against protozoa, viruses and fungi. It is characteristic that iodine is not absorbed from the mucous membrane, that is, there is no resorptive action.
Candles with Betadine are indicated in the complex therapy of endometritis, vaginitis and bacterial vaginosis, in case of trichomoniasis, candidal colpitis, and also as a prophylaxis before surgery.
The drug is administered once a day, deeply intravaginally, preferably at bedtime. For acute endometritis, twice daily administration is recommended for 7 days.
Advantages and disadvantages
Betadine helps not only with thrush, as it comes in the form of a solution, it is able to prevent the contamination of a clean wound with pathogenic flora, prevents the occurrence of wound infection in surgical and burn patients, with open injuries. Also, Betadine in solution can also be used not only intravaginally, but also to disinfect the skin around various probes, catheters and drains, for the treatment of bedsores and trophic ulcers. But Betadine is contraindicated in pregnancy and chronic renal failure, with excessive sensitivity to iodine, and in the pathology of the thyroid gland. Usually the drug is well tolerated, but sometimes individual intolerance occurs in the form of itching and allergies.
Zalain (sertaconazole)
Rating: 4.6
Sertaconazole is a highly effective fungicide derived simultaneously from imidazole and benzothiophene. It has a high activity against vaginal candidiasis, as well as staphylococci and streptococci. This drug increases the permeability of cell membranes of fungal structures, which destroys the parasite cells. Each intravaginal suppository contains 300 mg of sertaconazole nitrate.It is necessary to use the drug after washing the external genitalia once a day, before going to bed, deeply intravaginally. The most convenient to use candles, lying on his back.
Advantages and disadvantages
To apply the remedy for thrush Zalain need to once, but if necessary, you can repeat the introduction of a candle a week later. The unconditional advantages of Zalain include a single administration of the drug, the rare development of side effects, the absence of overdose symptoms. However, during treatment it is necessary to refuse sexual intercourse for several days after the administration of the suppository, but not because of the harmful effects of the drug on the partner, but because of the possibility of the spread of a candidal infection. Also during menstruation, you can freely treat with this drug.
McMiror Complex (nystatin + nifuratel)
Rating: 4.5
These intravaginal suppositories for thrush are a complex antifungal, antimicrobial drug, and a remedy for protozoa. Quite often there is a situation in which thrush is a co-infection, and the most important destructive effect of diseases such as trichomoniasis, chlamydia, and other infections. Therefore, McMiror is indicated primarily for the treatment of such conditions. It includes nifuratel as a derivative of nitrofuran, as well as the antifungal antibiotic nystatin. Apply McMiror daily before bedtime, inserting 1 candle deep into the vagina for 7 days. The Makmiror Complex is also produced in the form of a vaginal cream, which is used when necessary to treat children. The Makmiror complex is produced by the Italian pharmaceutical company Doppel Pharmaceuticals, and the cost of packing 8 vaginal suppositories, 500 mg each, starts at 630 rubles. in the prices of the summer of 2018.
Advantages and disadvantages
A positive effect is the effectiveness of trichomoniasis and chlamydia, higher compliance, that is, the possibility of using one tool instead of several, use once a day, as well as the presence of a creamy form. The disadvantages of McMiror include rare allergic reactions, which are most often represented by skin rash, individual drug intolerance, and low efficacy against anaerobic microflora. Thus, it is necessary to apply this drug locally only when infected with chlamydia infection, candidiasis and trichomonads.
The best ointments and creams for thrush
In addition to intravaginal suppositories, tablets and suppositories, there is an extensive range of drugs for the treatment of vaginal candidiasis in the form of ointments and creams. They have their own advantages, other than candles. For example, ointment and cream, unlike candles, act very quickly when applied to the surface of mucous membranes, since the rate of absorption of ointments and creams is much higher than that of candles.
It is when using ointments and creams that the unpleasant symptoms of a fungal infection, such as rashes, redness, swelling, and itching, are reduced more quickly. Also, ointments and creams can be used in men, which cannot be said about vaginal suppositories. Commercial creams and ointments occupy a more affordable price niche than intravaginal suppositories, and especially special intravaginal pills. In addition, ointment and cream is much easier to use than tablets and suppositories. A woman, and especially a man, does not need to take a special position, do not need to use applicators for reference, but simply distribute the ointment or cream on the surface of the vestibule and in its front third, and men should be applied to the head of the penis and the inner leaf the flesh.
Consider the most popular representatives for the treatment of vaginal candidiasis in the form of creams and ointments sold in Russian pharmacies.
Pimafucin (natamycin)
Rating: 4.9
The active ingredient of Pimafucin is the active antifungal antibiotic natamycin. This tool is embedded in the cell membranes of fungal structures, while they begin to break down and lose their strength. The point of application of natamycin is sterol groups.
Pimafucin can not only treat candidiasis. In addition to thrush, other representatives of yeast are sensitive to it, and the causative agents of dermatophytosis are less sensitive to it. Each gram of cream contains 20 mg of active ingredient in the form of natamycin.
In addition to thrush, the indications for the use of this cream include various candidal changes of the skin appendages (hair, nails), the remedy is used in the treatment of external otitis, which is complicated by candidiasis, as well as in various forms of ringworm.
Usually, the cream is applied with a strip of 2 to 3 cm long, once a day, and rubbed with slow movements. For uncomplicated vaginal candidiasis, the duration of the course does not exceed 7 or 10 days. In addition to the cream, Pimafucin can be produced in the form of enteric tablets, as well as in the form of vaginal suppositories. Pimafutsin is produced by Temmler, an Italian pharmaceutical company, and one package of cream weighing 30 g and a concentration of 2% natamycin can be purchased at a pharmacy for 271 rubles.
Advantages and disadvantages
Natamycin is a highly effective fungicide, and contraindications to its use are extremely limited, only in case of hypersensitivity to the components of the drug. Of the side effects, there is often a slight irritation, or a slight burning sensation that goes away itself, and does not require discontinuation of the drug. In the event that Pimafucin is used together with tablets for thrush, and the treatment is carried out under the supervision of a gynecologist, then in 89% of cases either recovery or persistent clinical remission with cleansing of the mucous membranes occurs.
Candide (clotrimazole)
Rating: 4.8
Candid vaginal cream containing 1% clotrimazole is produced by the famous Indian pharmaceutical company Glennmark Pharmaceuticals. Tuba cream weighing 20 g can have a cost of 203 rubles., The price range from 203 to 290 rubles in prices of August 2018.
Each gram of cream contains 10 mg of clotrimazole, a known fungicide. This cream interrupts the synthesis of the cell wall of fungi, which leads to their destruction. In addition to thrush, causative agents of various molds, varicolored lichens and erythrasma are very sensitive to the action of clotrimazole. In addition to vaginal candidiasis, the ointment is used to treat other fungal diseases, while the cream has a slight antiprotozoal and antibacterial effect. Apply the ointment on the mucous genital organs is necessary after the toilet. Apply it in a thin layer, rubbing it carefully and slowly. In the case of candidal vaginitis in women, Candide must be applied to the vaginal mucosa at least twice a day, morning and evening. In men, the drug is carefully rubbed into the head of the penis and the inner sheet of the foreskin after hygienic procedures, also 2 to 3 times a day. The course of treatment is determined by a gynecologist or a dermatovenerologist, but not less than 5 days, as part of complex therapy, and with monotherapy - not less than a week.
Advantages and disadvantages
The disadvantage of Candida is a sufficient degree of addiction of pathogens of fungal infections to clotrimazole. Still, Clotrimazole has been used for many years, and like all organisms that resist harmful substances, fungi gradually develop immunity to clotrimazole. But in uncomplicated cases, Candide quite effectively copes with thrush, especially in patients with a good voltage immunity. This drug has contraindications for use is pregnancy, hypersensitivity to clotrimazole, and for women with topical application - the period of menstruation.Clotrimazole can also cause various side effects, of which patients most often experience itching, hives, redness of the skin and slight burning sensation. It is also necessary to remember that this drug should in no case be applied to the skin near the eyes.
Ginofort cream (butoconazole)
Rating: 4.7
Ginofort vaginal cream, which is produced by the Hungarian pharmaceutical company Gedeon Richter, can be purchased in retail pharmacy at a price of 600 rubles. per package in 5 grams of the drug in a special case. The active substance is butaconazole. Each gram of vaginal cream contains 20 mg of active ingredient. In addition to the pathogens of thrush, this drug is active against the pathogen microsporia, trichophytes and athlete, and even some gram-positive microorganisms with a thick cell wall.
But still, it is preferable to use Ginofort precisely for candidiasis. It gradually accumulates in the cell membrane of the fungus, increases its permeability, which leads to the death of fungal cells. The cream for vaginal application is an emulsion, so the ability to adhere to the cells of the vaginal mucosa in butoconazole is increased. This leads to increased bioavailability, and sticking to the surface is called bioadhesion. As a result, with a single application of this cream, he is able to stay on the mucous membrane of the vagina and have a healing effect for at least 4 days. This drug is applied with an applicator once a day, at any time, regardless of the intake of other drugs.
Advantages and disadvantages
A great advantage of Gynofort cream for thrush is the ability of its prolonged stay on the vaginal mucosa after a single use. The relative disadvantage of Ginofort is a rather high price, which starts from 600 rubles, and varies for the same package to 770 rubles, as well as the possibility of irritation of the mucous membrane, after which it is necessary to stop treatment.
The best pills from thrush
In the treatment of any fungal disease, there are indications when only one local therapy, using suppositories, creams or ointments, will not be enough. In this case, oral medications for internal use, in capsules or tablets, which are able to create an active concentration of antifungal or fungicidal drug in the blood, are needed.
In that case, if the use of antifungal capsules or tablets is combined with local treatment, then the thrush will be attacked “from two sides” both from the surface of the mucous membrane or the skin, and from the bloodstream. It is this combination method of treatment that makes it possible to most quickly cope with the manifestations of candidiasis in patients with compromised immunity.
Diflucan (fluconazole)
Rating: 4.9
The drug Diflucan in capsules is produced by the pharmaceutical company Pfizer, USA, and one capsule with a dosage of 150 mg costs 200 rubles. In addition, 4 capsules are available at a price of 700 rubles. Diflucan is a highly effective drug for the treatment of genital candidiasis. The active ingredient is fluconazole, a modern fungicidal drug, with a high degree of activity against both the vegetative forms of the fungus and its spores.
The mechanism of action of the drug is to stop the synthesis of substances that make up its wall by a fungal cell. Thus, the fungal cell becomes fragile, and quickly destroyed. In addition to various forms of thrush, fluconazole is indicated for the treatment of cryptococcal infections, microsporia, and trichophytia. In the event that candidiasis has become disseminated, and has passed from mucous membranes to internal organs, then it is necessary to treat under the supervision of specialists, and take at least 400 mg on the first day of treatment, which should be long.In the case of uncomplicated vaginal candidiasis, this drug is taken only once - one capsule 150 mg.
Advantages and disadvantages
The advantages of tablets from thrush Diflucan include high chemical purity of the original substance, perfect compliance with uncomplicated forms of vaginal candidiasis, according to the type “accepted and forgotten”. But when treating with fluconazole, it is necessary to take into account the possibility of drug interactions with various anticoagulants, azithromycin, benzodiazepines, cytostatics, contraceptives and diuretic drugs, as well as a variety of antivirals and drugs for the treatment of asthma. Therefore, it is necessary treatment with fluconazole tablets must be performed only under the supervision of a physician.
Orungal, Irunin, (itraconazole)
Rating: 4.8
Orungal, a drug made by the renowned pharmaceutical company Janssen-Cilag, is one of the most expensive of all itraconazole preparations that exist on the domestic market. Compare yourself: packaging in 14 capsules of 100 mg will cost from 2300 rubles. for one package.
If we compare Orungal with other drugs of itraconazole, then the same package of Irunin will cost 690 rubles, Itrazola - 360 rubles, and itraconazole production of Ratiopharm - only 285 rubles. This is an Indian drug. Thus, it is possible to choose a preparation for any cost for your taste, but, of course, the effect will be different.
Orungal, he effectively and efficiently fights not only the various symptoms of candidiasis, both in nail and skin lesions, as well as in candidal stomatitis and vaginitis. Orungal is able to eliminate fungal sepsis, he fights with sporotrichosis, he is treated with cryptococcal pneumonia, pityriasis versicolor, and other various mycoses, including those with HIV infection. One capsule contains 100 mg of the active ingredient, and for banal vulvovaginal candidiasis, one capsule is swallowed whole immediately after a meal.
The treatment is carried out in the mildest cases by using 200 mg of the drug as a single injection, or therapy continues for 3 days with 200 mg of Orungal twice a day. In severe and systemic forms of candidiasis, such treatment can last up to 7 months.
Advantages and disadvantages
The remedy for thrush Orungal - one of the few highly effective fungicides, which is available in tablets. The image of Janssen-Cilag does not allow the release of funds from low-quality or low-quality substance, which has questionable effectiveness. But itraconazole has contraindications: in addition to hypersensitivity, it is very important for the patient to understand that if he has symptoms of chronic heart failure or signs of left ventricular dysfunction, then treatment with this drug should be urgently stopped. In the event that itraconazole and Orungal are used without a doctor's prescription, taking into account contraindications, sometimes, however, in rare cases, edema and symptoms of chronic heart failure have occurred. Orungal is also not used in patients with cirrhosis of the liver, in the case of chronic renal failure and in the age of children.
After the destruction of pathogenic microflora and fungi, cleaning the mucous membranes of the vagina and uterus from a fungal infection, it is necessary to restore the protective barriers of vaginal mucus, the protective function of the cervix, to eliminate the alkalization of the internal genitalia and increase acidity. Lactic acid is known to secrete vaginal lactobacilli, or Dederlein sticks. It is their disappearance that guarantees the free and unhindered introduction and reproduction of fungi. Therefore, after the treatment of vaginal candidiasis, it is necessary to start using preparations - eubiotics, which contain strains of prepared lactobacilli, as well as an auxiliary medium, which facilitates their settlement.
Attention! This rating is subjective, is not advertising and does not serve as a guide to the purchase. Before buying, you should consult with a specialist.
